Onyx Pharmaceuticals, Inc.
Ticker: ONXX 3031 Research Drive
Exchange: NASDAQ-National Market Richmond, California 94806
Industry: Manufacturing (510) 222-9700

Type of Shares:Common Shares Filing Date:4/15/96
U.S. Shares:2,500,000 Offer Date:5/9/96
Non-U.S. Shares:0 Filing Range:$11.00 - $13.00
Primary Shares:2,500,000 Offer Price:$12.00
Secondary Shares:0 Gross Spread:$0.84
Offering Amount: $30,000,000 Selling:$0.48
Expenses:$900,000 Reallowance:$0.10
Shares Out After:9,067,428

ManagerTierPhone
Montgomery SecuritiesLead Manager 4156272220
UBS Securities Inc.Co-manager (212) 230-4000

Auditor: Ernst & Young
Audited
Income
Latest
Unaudited
Income
Prior
Unaudited
Income
Balance
Sheet
12/31/95 3/31/96 3/31/95 3/31/96
Revenue:$6.95$1.97$1.36Assets:$14.33
Net Income:-$8.43-$2.29-$2.33Liabilities:$2.92
EPS:-$1.29-$0.35Equity:$11.42

Note: Dollar amounts are in U.S. millions; Audited figures expressed as full year,
unaudited figures are partial year

Business Description
The company is engaged in the discovery and development of novel therapeutics based upon the genetics of human disease, primarily cancer. The Company's goal is to capitalize on the discoveries of the past decade that have established cancer as a genetic-based disease. When certain genes are ,mutated, cells grow and proliferate unchecked and become resistant to internal mechanisms that would normally cause their death. The Company's drug discovery and development programs focus on innovative therapies which target the most frequent mutations causing cancer. Cancer is the second largest killer in the United States, accounting for over 22% of all deaths. The direct cost of treating cancer patients was estimated at $35 billion in 1995, with cancer drug costs totaling $3.0 billion. Of the estimated 1.3 million U.S. patients who are expected to be diagnosed with cancer in 1996, 780,000 or 60% are projected to die within 5 years.

Use of Proceeds
Proceeds from the offering will be used for research and development; capital expenditures; which may include a pilot scale manufacturing facility; and working capital and other general corporate purposes.

Last updated: 10/28/96

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