Virus Research Institute, Inc.
Ticker: VRII 61 Moulton Street
Exchange: NASDAQ-National Market Cambridge, Massachusetts 02138
Industry: Service (617) 864-6232

Type of Shares:Common Shares Filing Date:4/12/96
U.S. Shares:2,300,000 Offer Date:6/5/96
Non-U.S. Shares:0 Filing Range:$11.00 - $13.00
Primary Shares:2,300,000 Offer Price:$12.00
Secondary Shares:0 Gross Spread:$0.84
Offering Amount: $27,600,000 Selling:$0.48
Expenses:$800,000 Reallowance:$0.10
Shares Out After:8,793,511

ManagerTierPhone
Oppenheimer & Company, Inc.Lead Manager (212) 667-7402
Pacific Growth EquitiesCo-manager (415) 398-4563

Auditor: Eisner, Richard A.
Audited
Income
Latest
Unaudited
Income
Prior
Unaudited
Income
Balance
Sheet
12/31/95 3/31/96 3/31/95 3/31/96
Revenue:$1.96$0.56$0.07Assets:$2.30
Net Income:-$6.30-$1.37-$2.29Liabilities:$2.91
EPS:-$0.98-$0.21-$0.36Equity:-$0.61

Note: Dollar amounts are in U.S. millions; Audited figures expressed as full year,
unaudited figures are partial year

Business Description
The company is developer of vaccine delivery systems. The company is developing a polymer that can be combined with vaccines as an adjutant that boosts their effectiveness. These combinations, can be injected or administered through a nasal spray. Virus Research Institution , Inc. is engaged in the directory and development of vaccine delivery systems and improved and novel vaccines for adults and children. The company is developing a portfolio of proprietary vaccine delivery systems designed to improve the efficiency, lower the cost of administration and improve patient compliance for a variety of vaccine products. The company and its collaborators currently are applying the company's vaccine delivery systems to develop vaccines for the prevention of influenza, Lyme disease and Helicobacter pylori infections. The company has entered into long-term collaboration agreements with Pasteur Meriex Serums & Vaccins, a wholly-owned subsidiary of Rhone Poulenc S.A., pursuant to which Pasteur Merieux may utilize the company's vaccine delivery systems in developing a number of vaccines.

Use of Proceeds
The proceeds from the proposed offering will be used to repay debt, to finance research and development and for working capital and other general corporate purposes.

Last updated: 10/28/96

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