AutoCyte, Inc.
Ticker:ACYT 112 Orange Drive
Exchange:NASDAQ-National Market Elon College, NC 27244
Industry:Manufacturing (SIC Code 3826) (910) 584-0250

Offering Information
Type of Shares:Common Shares Filing Date:6/27/97
U.S. Shares:3,100,000 Offer Date:9/4/97
Non-U.S. Shares:0 Filing Range:$10.00 - $12.00
Primary Shares:3,100,000 Offer Price:$10.00
Secondary Shares:0 Gross Spread:$0.70
Offering Amount: $34,100,000 Selling:$0.42
Expenses:$885,000 Reallowance:$0.10
Shares Out After:12,261,324

Primary Underwriting Group
ManagerTierPhone
Dillon, Read & Co. Inc.Lead Manager (212) 906-7523
UBS Securities Inc.Co-manager (212) 821-4510

Legal Counsel, Auditor and Registrar
Issuer's Law Firm: Palmer & Dodge
Bank's Law Firm: Mintz, Levin, Cohn, Ferris, Glovsky And Popeo
Auditor: Ernst & Young
Registrar/Transfer Agent: American Stock Transfer & Trust Co

Selected Financial Data

Dollar amounts in U.S. millions except for per share data
3 Month Ending Financials
Full Year
Audited
Income
Latest
Unaudited
Income
Prior
Unaudited
Income
Balance
Sheet
12/31/96 3/31/97 3/31/96 3/31/97
Revenue:$1.75$0.38$0.60Assets:$11.58
Net Income:-$16.92-$2.23-$1.34Curr Assets:
EPS:-$0.22Liabilities:$1.63
Prior EPS:-$1.61-$0.49Curr Liabilities:
Cash Flow/Oper:Equity:$9.96
Cash Flow/Fin:Cash:
Cash Flow/Inv:

Business Description
The company develops, manufactures and markets the only integrated sample preparation and automated image analysis system to support cytologists in cervical cancer screening. The company's integrated system is comprised of the AutoCyte PREP sample preparation system and the AutoCyte SCREEN automated image analysis system. PREP is a proprietary automated liquid-based sample preparation system that produces slides with a homogeneous layer, or "monolayer," of cervical cells. The company believes PREP improves laboratory productivity and significantly reduces interpretation errors by producing cell samples that are clearer, more uniform and easier to interpret than conventional Pap smear samples. PREP is designed to operate both as an independent diagnostic system. SCREEN is an automated image analysis system which combines proprietary imaging technology and classification software with off-the-shelf computer hardware to screen slides prepared using PREP. SCREEN is designed to be an interactive support tool for the cytology professional in the primary screening of cervical cells. By designing PREP and SCREEN to function together, the company has developed a system which the company believes will operate with higher throughput and greater diagnostic sensitivity than the conventional Pap smear test and other automated image analysis systems.

Competition
The Company's competitors in the development and commercialization of alternative cervical cancer screening technologies include both publicly traded and privately held companies. The alternative technologies known to the Company have focused on improvements in slide sample preparation, the development of automated, computerized screening systems and adjunctive testing technologies. To date, the Company knows of no competitor which has developed an integrated sample preparation and image analysis system, such as PREP and SCREEN which have been designed to function together. Nevertheless, some competitors' products have already received FDA approval and are being marketed. In addition, certain of the Company's competitors have substantially greater financial, marketing, sales, distribution and technical resources than the Company, and more experience in research and development, clinical trials, regulatory matters, customer support, manufacturing and marketing. In addition, some of these companies may have received third-party reimbursement for their products. The Company believes that its products will compete on the basis of a number of factors, including slide specimen adequacy, screening sensitivity, ease of use, efficiency, cost to customers and nature of claims allowed by the FDA. While the Company believes that its products will have competitive advantages based on some of these factors, there can be no assurance that various competitors' products will not have competitive advantages based on other factors that, when coupled with the earlier market entry of some products, will adversely effect the market acceptance of PREP and SCREEN. Moveover, there can be no assurance that the Company will be able to compete successfully against current or future competitors or that competition, including the development and commercialization of new products and technologies, will not have a material adverse effect on the Company's business, financial condition and results of operations. The Company's products could be rendered obsolete or uneconomical by technological advances of the Company's current or potential competitors, the introduction and market acceptance of competing products or by other approaches.

Business Plan
The Company expects to commence marketing PREP and SCREEN in the United States for cervical cancer screening when and if FDA approval for cervical cancer screening is obtained. PREP is designed to be sold as either a stand-alone system or as an integrated system with SCREEN. The Company intends to achieve market acceptance of PREP alone and then to target its PREP customer base for its initial marketing efforts of SCREEN. The Company's marketing strategy is to achieve broad market acceptance for the integrated PREP and SCREEN system for cervical cancer screening.

Use of Proceeds
The proceeds from the proposed offering will be used to fund sales and marketing activities, research and development, capital expenditures, clinical trials, working capital requirements and other general corporate purposes.

Principal and Selling Shareholders
Name of Shareholder% Owned
Before
% Owned
After
Roche Image Analysis Systems, Inc.33.30%24.90%
Sprout Capital VII, L.P.21.90%16.40%
Robert E. Curry, Ph.D.21.90%16.40%
Richard A. Charpie, Ph.D.21.90%16.40%
Ampersand Specialty Materials and Chemicals III Limited Partnership21.90%16.40%
James B. Powell, M.D.21.60%16.20%
Allemanni, LLC21.60%16.40%
Note: Represents ownership of 5% or more prior to the offering.
Executive Officers and Directors
Officer NameTitleAge
Richard A. Charpie, Ph.D.Chairman of the Board45
William O. GreenChief Financial Officer, Vice President of Finance and Treasurer39
Thomas P. Mac MahonDirector50
Susan E. WhiteheadDirector43
Robert E. Curry, Ph.D.Director50
Ernest A. KneselExecutive Vice President51
James B. Powell, M.D.President, Chief Executive Officer and Director58
Thomas Gahm, Ph.D.Vice President of Computer Science41
James W. Geyer, Ph.D.Vice President of Laboratory Science52
Eric W. LinsleyVice President of Operations and Business Development35
Steven C. McPhailVice President of Sales and Marketing43

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