Medical Science Systems, Inc.
Ticker:MSSI 4400 Macarthur Boulevard, Suite 980
Exchange:American Stock Exchange Newport Beach, CA 92660
Industry:Service (SIC Code 8099) (714) 440-9730
# of Employees:27

Offering Information
Type of Shares:Common Shares Filing Date:10/8/97
U.S. Shares:1,800,000 Offer Date:11/25/97
Non-U.S. Shares:0 Filing Range:$8.00 - $9.00
Primary Shares:1,800,000 Offer Price:$9.00
Secondary Shares:0 Gross Spread:$0.72
Offering Amount: $15,300,000 Selling:$0.41
Expenses: - Reallowance:$0.10
Shares Out After:5,238,007

Primary Underwriting Group
ManagerTierPhone
Nutmeg Securities, Inc.Lead Manager (800) 288-5513
Millennium Securities Corp.Co-manager

Legal Counsel, Auditor and Registrar
Issuer's Law Firm: Jeffers, Wilson, Shaff & Falk, LLP
Bank's Law Firm: Prifti, William M.
Auditor: Greenbaum & Goldstein LLP
Registrar/Transfer Agent: U. S. Stock Transfer Corporation

Selected Financial Data

Dollar amounts in U.S. millions except for per share data
6 Month Ending Financials
Full Year
Audited
Income
Latest
Unaudited
Income
Prior
Unaudited
Income
Balance
Sheet
12/31/96 6/30/97 6/30/96 6/30/97
Revenue:$1.92$0.10$1.86Assets:$0.41
Net Income:-$0.79-$1.83$0.52Curr Assets:$0.07
EPS:-$0.18-$0.43$0.12Liabilities:$1.43
Prior EPS:$0.03-$1.39$0.54Curr Liabilities:$0.86
Cash Flow/Oper:-$0.44$1.45$0.09Equity:-$1.01
Cash Flow/Fin:$0.57-$0.09-$0.04Cash:$0.03
Cash Flow/Inv:-$0.15-$0.09Working Cap:-$0.79

Business Description
The company has developed genetically susceptibility testing services for common diseases which are treatable and preventable. The company is focused on four diseases, periodontitis, osteoporosis, coronary artery and diabetic retinopathy.

Use of Proceeds
The proceeds from the proposed offering will be used for marketing, sales, customer service and commercialization expenses, research and development activities, capital investment, repayment of bridge loans, and working capital and general corporate purposes.

Additional Underwriter Compensation
Warrant to purchase 150,000 shares/units at a nominal price.

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